Formulation: A solid
Formal Name: 1-((9H-carbazol-4-yl)oxy)-3-((propan-2-yl-d7)amino)propan-2-ol
Purity: ≥99% deuterated forms (d1-d7)
Formula Markup: C18H15D7N2O2
Formula Weight: 305,4
Shelf life (days): 1460
CAS Number: 1173021-02-7
Notes: Carazolol-d7 is intended for use as an internal standard for the quantification of carazolol (Item No. 18628) by GC- or LC-MS. Carazolol is a β-adrenergic receptor (β-AR) ligand (Kds = 0.2, 0.03, and 4.47 nM for the human β1-, β2-, and β3-ARs, respectively).{65091} It reduces epinephrine-induced increases in mean arterial blood pressure and heart rate in conscious pigs when administered at a dose of 10 µg/kg.{65092} Carazolol has been found in wastewater effluent.{65093} Formulations containing carazolol have been used to reduce stress in livestock during transport.