Carbinoxamine-d6 (maleate), CAS 2747914-08-3

Formulation: A solid

Formal Name: 2-[(4-chlorophenyl)-2-pyridinylmethoxy]-N,N-di(methyl-d3)-ethanamine, (2Z)-2-butenedioate

Purity: ≥99% deuterated forms (d1-d6)

Formula Markup: C16H13ClD6N2O • C4H4O4

Formula Weight: 412,9

Shelf life (days): 1460

CAS Number: 2747914-08-3

Notes: Carbinoxamine-d6 is intended for use as an internal standard for the quantification of carbinoxamine (Item No. 23937) by GC- or LC-MS. Carbinoxamine is a competitive histamine H1 receptor antagonist (Ki = 2.3 nM) and first generation antihistamine.{23220} It is also an L-type calcium channel inhibitor (Ki = 1.08 nM).{41288} Carbinoxamine decreases negative inotropic activity in isolated guinea pig left atria and negative chronotropic activity in guinea pig spontaneously beating isolated right atria (EC50s = 250 and 480 nM, respectively). Formulations containing carbinoxamine have been used in the treatment of allergic rhinitis.

• Artikelnummer: CAY34246-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34246-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung