Carbinoxamine (maleate), CAS 3505-38-2

Formulation: A solid

Formal Name: 2-[(4-chlorophenyl)-2-pyridinylmethoxy]-N,N-dimethyl-ethanamine, (2Z)-2-butenedioate

Purity: ≥98%

Formula Markup: C16H19ClN2O • C4H4O4

Formula Weight: 406,9

Shelf life (days): 1460

CAS Number: 3505-38-2

Notes: Carbinoxamine is a competitive histamine H1 receptor antagonist (Ki = 2.3 nM) and first generation antihistamine.{23220} It also competes with [3H]diltiazem, an L-type calcium channel blocker, for binding to the benzothiazepine site on rat cardiomyocytes (Ki = 1.08 nM).{41288} Carbinoxamine decreases negative inotropic activity in isolated guinea pig left atria by 76% (EC50 = 250 nM) and negative chronotropic activity in guinea pig spontaneously beating isolated right atria (EC50s = 250 and 480 nM, respectively) by 48% compared with control. Formulations containing carbinoxamine have been used in the treatment of allergic rhinitis.

• Artikelnummer: CAY23937-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23937-1
• Green Labware: Nein
• Verpackungseinheit: 1 g
• Mengeneinheit: STK