Formulation: A solution in acetonitrile
Formal Name: 4-[[[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]methyl]amino]-benzeneacetic acid
Purity: ≥98%
Formula Markup: C28H25Cl3N2O4
Formula Weight: 559,9
Shelf life (days): 365
CAS Number: 2522599-79-5
Notes: CAY10771 is a dual agonist of farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor δ (PPARδ).{59497} It activates FXR and PPARδ in reporter assays using HEK293T cells (EC50s = 0.94 and 1.5 µM, respectively) and is selective for these receptors over retinoic acid receptor α (RARα), retinoid X receptor α (RXRα), PPARα, PPARγ, and liver X receptor α (LXRα) at 10 µM.