Formulation: A lyophilized powder
Formal Name: L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide
Purity: ≥95%
Formula Markup: C45H57N9O10S2
Formula Weight: 948,1
Shelf life (days): 1460
CAS Number: 47910-79-2
Notes: CCK (27-33) is a C-terminal fragment of CCK (Item Nos. 23371 / 24404), a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety.{40607,40606} Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 µM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 µM), an effect that can be reversed by naloxone.{39623} Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in mice when administered at doses up to 1 µmol/kg.{39624}