CCR2-RA-(R), CAS 512177-83-2

CCR2-RA-(R), CAS 512177-83-2
Artikelnummer
CAY28423-1
Verpackungseinheit
1 mg
Hersteller
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: (5R)-4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one

Purity: ≥95%

Formula Markup: C18H19ClFNO3

Formula Weight: 351,8

Shelf life (days): 1460

CAS Number: 512177-83-2

Notes: CCR2-RA-[R] is an allosteric antagonist of chemokine (C-C motif) receptor 2 (CCR2; IC50 = 103 nM).{50108,50109,50110} It inhibits [35S]GTPγS binding and β-arrestin recruitment induced by chemokine (C-C motif) ligand 2 (CCL2) in U2OS membranes and cells, respectively, expressing CCR2 (IC50s = 24 and 25 nM, respectively).{50108}
Mehr Informationen
Artikelnummer CAY28423-1
Hersteller Cayman Chemical
Hersteller Artikelnummer 28423-1
Green Labware Nein
Verpackungseinheit 1 mg
Mengeneinheit STK
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