CFMTI, CAS 864864-17-5

Formulation: A solid

Formal Name: 2-cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one

Purity: ≥90%

Formula Markup: C19H16FN5O

Formula Weight: 349,4

Shelf life (days): 1460

CAS Number: 864864-17-5

Notes: CFMTI is a metabotropic glutamate receptor 1 (mGluR1) allosteric antagonist (IC50 = 2.6 nM in CHO cells expressing the human receptor).{66304,66303} It is selective for mGluR1 over mGluR5 by greater than 2,000-fold, as well as over mGluR2, -4, -6, -7, or -8 at 10 µM in CHO cells expressing the human receptors.{66303} CFTMI reduces methamphetamine-induced hyperlocomotion in mice when administered orally at doses ranging from 1 to 10 mg/kg.

• Artikelnummer: CAY37546-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37546-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe