CGP 36742, CAS 123690-78-8

Formulation: A solid

Formal Name: P-(3-aminopropyl)-P-butyl-phosphinic acid

Purity: ≥95%

Formula Markup: C7H18NO2P

Formula Weight: 179,2

Shelf life (days): 1460

CAS Number: 123690-78-8

Notes: CGP 36742 is an antagonist of GABAB receptors (IC50 = 36 µM).{61872} It is selective for GABAB over a panel of 11 receptors, including GABAA, at 1 mM. CGP 36742 (3 mg/kg) reduces paired-pulse inhibition of the late inhibitory postsynaptic potential (IPSP) in CA1 pyramidal neurons in rats. It increases latency to step-down in a passive avoidance test in mice in a dose-dependent manner.{61873} CGP 36742 (10 and 30 mg/kg) decreases immobility time in the forced swim test in mice.{61874}

• Artikelnummer: CAY35495-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35495-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK
• Methode: Reinstoffe