Chlorpheniramine (maleate), CAS 113-92-8

Formulation: A crystalline solid

Formal Name: γ-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine, 2Z-butenedioate

Purity: ≥95%

Formula Markup: C16H19ClN2 • C4H4O4

Formula Weight: 390,9

Shelf life (days): 1460

CAS Number: 113-92-8

Notes: Chlorpheniramine is a histamine H1 receptor antagonist with an IC75 value of 0.0016 μg/ml for reversal of histamine-induced spasms in isolated guinea pig ileum.{39804} It protects against intravenous histamine-induced death (PD50 = 0.15 mg/kg) and delays induction of aerosolized histamine-induced coughing (ED100sec = 0.44 mg/kg) in guinea pigs. Chlorpheniramine (20 mg/kg, i.p.) prevents histamine-induced passive cutaneous anaphylaxis (PCA) in rabbits.{39805} It also reduces respiratory resistance and hypersecretion of tracheobronchial fluid in a dog model of histamine-induced asthma.{39806} Formulations containing chlorpheniramine have been used in the treatment of seasonal allergies.

• Artikelnummer: CAY21253-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21253-50
• Green Labware: Nein
• Verpackungseinheit: 50 g
• Mengeneinheit: STK