Chlorzoxazone-d3, CAS 1185173-60-7

Formulation: A solid

Formal Name: 5-chloro-2(3H)-benzoxazolone-4,6,7-d3

Purity: ≥99% deuterated forms (d1-d3)

Formula Markup: C7HClD3NO2

Formula Weight: 172,6

Shelf life (days): 1460

CAS Number: 1185173-60-7

Notes: Chlorzoxazone-d3 is intended for use as an internal standard for the quantification of chlorzoxazone (Item No. 18869) by GC- or LC-MS. Chlorzoxazone is a centrally acting muscle relaxant and an activator of small and intermediate conductance calcium-activated potassium channels (EC50s = 87 and 98 µM for KCa2.2 and KCa3.1, respectively).{27789,23031} In vivo, chlorzoxazone (10 mg/kg) decreases alcohol, but not water, intake in a dose-dependent manner and reduces the propensity for rapid initial alcohol intake in rats with intermittent, but not continuous, access to alcohol.{43334} Formulations containing chlorzoxazone have been used in the treatment of pain and stiffness caused by muscle spasm.

• Artikelnummer: CAY34237-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34237-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung