Cilengitide, CAS 188968-51-6

Formulation: A crystalline solid

Formal Name: cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-N-methyl-L-valyl)

Purity: ≥98%

Formula Markup: C27H40N8O7

Formula Weight: 588,7

Shelf life (days): 1460

CAS Number: 188968-51-6

Notes: Cilengitide is a cyclo-(Arg-Gly-Asp-D-Phe-Val) (cRGDfV) peptide and integrin αVβ3 receptor antagonist.{39378} It inhibits adhesion and induces apoptosis of U87MG and U373MG malignant glioma (MG) cells, but not U251MG cells that lack the integrin αVβ3 receptor, in vitro at a concentration of 20 μg/ml. Cilengitide (200 μg/animal per day) delays tumor implantation time, reduces tumor growth, and prolongs survival in a U87MG mouse model of glioblastoma.{39379}

• Artikelnummer: CAY22289-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22289-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK