Ciprofibrate-d6, CAS 2070015-05-1

Formulation: A solid

Formal Name: 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-d3-propanoic-3,3,3-d3 acid

Purity: ≥99% deuterated forms (d1-d6)

Formula Markup: C13H8Cl2D6O3

Formula Weight: 295,2

Shelf life (days): 1460

CAS Number: 2070015-05-1

Notes: Ciprofibrate-d6 is intended for use as an internal standard for the quantification of ciprofibrate (Item No. 18515) by GC- or LC-MS. Ciprofibrate is an agonist of peroxisome proliferator-activated receptor α (PPARα; EC50 = 0.9 µM in a transactivation assay).{61725} It is selective for PPARα over PPARγ and PPARδ at 300 µM.{7009} Ciprofibrate (250 µM) induces cell cycle arrest at the G2/M and S phases in Fao rat, but not HepG2 human, hepatocellular carcinoma cells.{61726} It decreases fasting plasma levels of triglycerides and increases fasting plasma glucose levels in the apolipoprotein CIII transgenic mouse model of hypertriglyceridemia when administered at a dose of 10 mg/kg.{29848} Formulations containing ciprofibrate have been used in the treatment of hypertriglyceridemia.

• Artikelnummer: CAY33917-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33917-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung