Cirsimaritin, CAS 6601-62-3

Formulation: A solid

Formal Name: 5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one

Purity: ≥90%

Formula Markup: C17H14O6

Formula Weight: 314,3

Shelf life (days): 1460

CAS Number: 6601-62-3

Notes: Cirsimaritin is a flavone that has been found in D. kotschyi and has diverse biological activities.{58726,58727,58728,58729,58730} It binds to rat adenosine A1, rat A2A, and human A3 receptors (Kis = 1.2, 3, and 1.72 µM, respectively, in radioligand binding assays), as well as inhibits dipeptidyl peptidase 4 (DPP-4; IC50 = 0.43 µM).{58726,58727} Cirsimaritin is active against the chloroquine-sensitive NF54 strain of P. falciparum (IC50 = 16.9 µM).{58728} It inhibits the proliferation of AGS, HT-29, Saos-2, and WEHI 164 cells (IC50s = 14.4, 13.1, 38.5, and 40.7 µM, respectively).{58729} Cirsimaritin (10 mg/kg) increases the number of entries into, and percentage of time spent in, the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity.{58730}

• Artikelnummer: CAY34498
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34498-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK