Formulation: A crystalline solid
Formal Name: cis-1-amino-1,3-cyclobutanedicarboxylic acid
Purity: ≥95%
Formula Markup: C6H9NO4
Formula Weight: 159,1
Shelf life (days): 1460
CAS Number: 73550-55-7
Notes: cis-ABCD is an NMDA receptor agonist.{54689} It binds to NMDA receptors (Ki = 0.052 µM) and is selective for NMDA over kainate and AMPA receptors in radioligand binding assays (Kis = >300 µM for both). cis-ABCD induces inward currents in Xenopus oocytes expressing rat NMDA receptors (EC50 = 1.26 µM), an effect that can be blocked by the NMDA receptor antagonist D-2-amino-7-phosphonoheptanoate (D-AP7). In vivo, cis-ABCD (30 and 70 nmol/animal) induces contralateral turning in rats.{54690}