Notes: Clobetasol propionate is a corticosteroid.{33297} It binds to glucocorticoid receptors in a cell-free assay (IC50 = 3.17 nM) and inhibits proliferation of primary human skin fibroblasts when used at a concentration of 5 µg/ml.{33297,52985} Topical administration of clobetasol propionate reduces croton oil-induced ear edema in mice.{33297} Formulations containing clobetasol propionate have been used in the treatment of inflammatory skin conditions.