Clobetasol Propionate-d5, CAS 2280940-18-1

Formulation: A solid

Formal Name: 21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy-2,2,3,3,3-d5)-(11β,16β)-pregna-1,4-diene-3,20-dione

Purity: ≥99% deuterated forms (d1-d5)

Formula Markup: C25H27ClD5FO5

Formula Weight: 472

Shelf life (days): 1460

CAS Number: 2280940-18-1

Notes: Clobetasol propionate-d5 is intended for use as an internal standard for the quantification of clobetasol propionate (Item No. 21251) by GC- or LC-MS. Clobetasol propionate is a corticosteroid.{33297} It binds to glucocorticoid receptors in a cell-free assay (IC50 = 3.17 nM) and inhibits proliferation of primary human skin fibroblasts when used at a concentration of 5 µg/ml.{33297,52985} Topical administration of clobetasol propionate reduces croton oil-induced ear edema in mice.{33297} Formulations containing clobetasol propionate have been used in the treatment of inflammatory skin conditions.

• Artikelnummer: CAY33365-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33365-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung