Corylifol A, CAS 775351-88-7

Formulation: A solid

Formal Name: 3-[3-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-4-hydroxyphenyl]-7-hydroxy-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C25H26O4

Formula Weight: 390,5

Shelf life (days): 1460

CAS Number: 775351-88-7

Notes: Corylifol A is a flavonoid that has been found in P. corylifolia and has diverse biological activities.{63218,63219,31782,63220} It inhibits the activity of carboxylesterase 2 (CES2; Ki = 0.62 µM for the human enzyme), as well as induces estrogen receptor α (ERα) and ERβ transcriptional activation in reporter assays using HeLa cells when used at concentrations ranging from 0.1 to 10 µM.{63219,31782} Corylifol A is cytotoxic to (IC50 = 13.5 µg/ml), and inhibits IL-6-induced STAT3 promoter activity in (IC50 = 0.81 µM in a reporter assay), Hep3B hepatocellular carcinoma cells.{63220,63218}

• Artikelnummer: CAY34616-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34616-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK