CP 775,146, CAS 702680-17-9

CP 775,146, CAS 702680-17-9
Artikelnummer
CAY28290-1
Verpackungseinheit
1 mg
Hersteller
Cayman Chemical

Verfügbarkeit: wird geladen...
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Formulation: A solid

Formal Name: 2-methyl-2-[3-[(3S)-1-[2-[4-(1-methylethyl)phenyl]acetyl]-3-piperidinyl]phenoxy]-propanoic acid

Purity: ≥95%

Formula Markup: C26H33NO4

Formula Weight: 423,5

Shelf life (days): 1460

CAS Number: 702680-17-9

Notes: CP 775,146 is an agonist of peroxisome proliferator-activated receptor α (PPARα) that selectively binds to PPARα (Ki = 24.5 nM) over PPARβ and PPARγ (Kis = >10,000 nM).{51044} CP 775,146 induces PPARα transcriptional activity in a reporter assay (EC50s = 57 and 284 nM for human and rat receptors, respectively, expressed in HepG2 cells). It decreases plasma triglyceride levels in mice by 73% when administered at a dose of 2 mg/kg per day for two days.
Mehr Informationen
Artikelnummer CAY28290-1
Hersteller Cayman Chemical
Hersteller Artikelnummer 28290-1
Green Labware Nein
Verpackungseinheit 1 mg
Mengeneinheit STK
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