CU-CPT4a, CAS 1279713-77-7

Formulation: A solid

Formal Name: N-[(3-chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine

Purity: ≥98%

Formula Markup: C18H13ClFNO3S

Formula Weight: 377,8

Shelf life (days): 1460

CAS Number: 1279713-77-7

Notes: CU-CPT4a is a toll-like receptor 3 (TLR3) antagonist (IC50 = 3.44 µM).{36228} It is selective for TLR3 over TLR4, TLR2/6, TLR1/2, and TLR7 at 27 µM. CU-CPT4a inhibits dsRNA binding to TLR3 with a Ki value of 2.96 µM in a fluorescence anisotropy assay. It decreases poly(I:C)-induced production of TNF-α and IL-1β in RAW 264.7 cells when used at a concentration of 27 µM.

• Artikelnummer: CAY30951-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 30951-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK