Deltorphin II (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-tyrosyl-D-alanyl-L-phenylalanyl-L-α-glutamyl-L-valyl-L-valyl-glycinamide, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C38H54N8O10 • XCF3COOH

Formula Weight: 782,9

Shelf life (days): 1460

Notes: Deltorphin II is a peptide agonist of δ2-opioid receptors.{25533,37715} It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 µM, respectively) and induces [35S]GTPγS binding in mouse brain membrane preparations (EC50 = 0.034 µM). Deltorphin II (0.12 mg/kg) decreases the infarction zone:risk zone ratio in a rat model of myocardial ischemia-reperfusion injury induced by coronary occlusion, an effect that can be reversed by the δ2-opioid receptor antagonist naltriben but not the δ1-opioid receptor antagonist BNTX.{62411} Intrathecal administration of deltorphin II (15 µg/animal) increases latency to withdraw in the paw pressure and tail-flick tests in rats.{46878}

• Artikelnummer: CAY34691-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34691-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK