Desglymidodrine, CAS 3600-87-1

Formulation: A solid

Formal Name: α-(aminomethyl)-2,5-dimethoxy-benzenemethanol

Purity: ≥98%

Formula Markup: C10H15NO3

Formula Weight: 197,2

Shelf life (days): 1460

CAS Number: 3600-87-1

Notes: Desglymidodrine is the active metabolite of the prodrug midodrine (Item No. 17349).{62783} It is formed from midodrine by enzymatic hydrolysis.{62246} Desglymidodrine is an agonist of α1-adrenergic receptors (α1-ARs).{62783} It binds to α1-ARs (Kis = 9.77, 9.55, and 8.51 µM for α1A, α1B, and α1D-ARs, respectively) and increases intraurethral pressure (IUP) and mean arterial pressure (MAP) by 5 and 20 mm Hg, respectively, in anesthetized dogs at doses of 205 and 250 nmol/kg, respectively.

• Artikelnummer: CAY35608-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35608-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe