DFB, CAS 15332-10-2

Formulation: A solid

Formal Name: 2-[(3-fluorophenyl)methylene]hydrazone, 3-fluoro-benzaldehyde

Purity: ≥95%

Formula Markup: C14H10F2N2

Formula Weight: 244,2

Shelf life (days): 1460

CAS Number: 15332-10-2

Notes: DFB is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGluR5).{63119} It potentiates glutamate-, quisqualate-, or 3,5-dihydroxyphenylglycine-induced calcium transients in CHO cells expressing human mGluR5 (EC50s = 0.021, 0.642, and 2.4 µM, respectively). It also enhances quisqualate-induced phosphatidylinositol hydrolysis in rat hippocampal slices (EC50 = 0.42 µM). DFB improves spatial alternation retention in the Y-maze special alternation task in rats.{63120}

• Artikelnummer: CAY34395-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34395-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK