diABZI STING Agonist 2, CAS 2138300-40-8

Formulation: A solid

Formal Name: 1,1′-(1,4-butanediyl)bis[2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-1H-benzimidazole-5-carboxamide

Purity: ≥98%

Formula Markup: C34H38N12O4

Formula Weight: 678,7

Shelf life (days): 1460

CAS Number: 2138300-40-8

Notes: diABZI STING agonist 2 is an agonist of stimulator of interferon genes (STING).{43612} It binds to STING with an apparent Kd value of 1.6 nM. It is selective for STING over the acute phase reactant orosomucoid 1 (ORM1; apparent Kd = 79 nM). diABZI STING agonist 2 increases phosphorylation of interferon regulatory factor 3 (IRF3) and STING in human peripheral blood mononuclear cells (PBMCs). It also induces secretion of IFN-β from PBMCs (EC50 = 3.1 µM).

• Artikelnummer: CAY34088-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34088-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK