Dicyclomine (hydrochloride), CAS 67-92-5

Formulation: A solid

Formal Name: [1,1'-bicyclohexyl]-1-carboxylic acid, 2-(diethylamino)ethyl ester, monohydrochloride

Purity: ≥98%

Formula Markup: C19H35NO2 • HCl

Formula Weight: 346

Shelf life (days): 1460

CAS Number: 67-92-5

Notes: Dicyclomine is an M1 and M2 muscarinic acetylcholine receptor antagonist (Kis = 3.16 and 44.7 nM, respectively).{41413} It inhibits inositol phosphate accumulation induced by the non-selective acetylcholine agonist carbamoylcholine (carbachol; Item No. 14486) in guinea pig cortex (Ki = 12 nM; pA2 = 7.88). Dicyclomine (10 mg/kg, i.v.) inhibits potassium-induced contraction of ileum, colon, and duodenum in anesthetized rats by 21.85, 30.81, and 37.86%, respectively.{41414} Formulations containing dicyclomine have been used to treat functional and irritable bowel syndrome and to relieve muscle spasms in the gastrointestinal tract.

• Artikelnummer: CAY23867-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23867-1
• Green Labware: Nein
• Verpackungseinheit: 1 g
• Mengeneinheit: STK