DL-3,4-Dihydroxyphenyl glycol, CAS 28822-73-3

Formulation: A solid

Formal Name: 4-(1,2-dihydroxyethyl)-1,2-benzenediol

Purity: ≥90%

Formula Markup: C8H10O4

Formula Weight: 170,6

Shelf life (days): 1460

CAS Number: 28822-73-3

Notes: DL-3,4-Dihydroxyphenyl glycol is an active metabolite of the endogenous neurotransmitter norepinephrine (Item No. 35580).{68188} It is produced by the deamination of norepinephrine by monoamine oxidase (MAO) in the cytosol.{68189} DL-3,4-Dihydroxyphenyl glycol scavenges DPPH (Item No. 14805) radicals in a cell-free assay (IC50 = 1.55 µM).{68187} It reduces LPS-induced nitrite production in isolated mouse peritoneal macrophages when used at concentrations of 50 and 100 µM. DL-3,4-Dihydroxyphenyl glycol (50 and 100 µM) decreases increases in inducible nitric oxide synthase (iNOS) and COX-2 levels induced by LPS in isolated mouse macrophages. It also inhibits LPS-induced degradation of IκBα in isolated mouse macrophages.

• Artikelnummer: CAY11708-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 11708-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe