DPC-AJ1951 (trifluoroacetate salt)

Formulation: A solid

Formal Name: 2-methylalanyl-L-valyl-2-methylalanyl-L-α-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-norleucyl-L-histidyl-L-glutaminyl-L-arginyl-L-alanyl-L-lysyl-L-tyrosinamide, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C76H127N23O19 • XCF3COOH

Formula Weight: 1667

Shelf life (days): 1460

Notes: DPC-AJ1951 is a peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR; EC50 = 0.15 nM in HEK293 cells expressing human PPR).{43338} It induces cAMP production in SAOS-2 and UMR106 cells that endogenously express human and rat PPR, respectively (EC50s = 2.2 and 1.1 nM, respectively). DPC-AJ1915 stimulates osteoclast-mediated bone resorption in fetal rat long-bone explant cultures and increases collagen synthesis and cell proliferation in neonatal mouse parietal bone explants. In vivo, DPC-AJ1951 normalizes serum calcium levels in thyroidparathyroidectomized rats.

• Artikelnummer: CAY25343-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25343-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK