(E/Z)-Endoxifen, CAS 110025-28-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol

Purity: ≥98% (mixture of isomers)

Formula Markup: C25H27NO2

Formula Weight: 373.5

CAS Number: 110025-28-0

Notes: (E/Z)-Endoxifen is a mixture of (E)-endoxifen and (Z)-endoxifen.{29622} (Z)-Endoxifen is an active metabolite of the estrogen receptor antagonist tamoxifen (Item Nos. 13258 / 11629) and is formed from tamoxifen primarily by the cytochrome P450 (CYP) isoform CYP2D6 via an N-desmethyltamoxifen (Item No. 40673) intermediate.{28446} (Z)-Endoxifen (100 nM) inhibits 17β-estradiol-induced increases in mRNA encoding the progesterone receptor in MCF-7 breast cancer cells.{67256} (E)-Endoxifen is a potential impurity in commercial preparations of (Z)-endoxifen.{72413}

• Artikelnummer: CAY21502-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21502-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK