(E/Z)-Endoxifen, CAS 110025-28-0

Formulation: A crystalline solid

Formal Name: 4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol

Purity: ≥98% (mixture of isomers)

Formula Markup: C25H27NO2

Formula Weight: 373,5

Shelf life (days): 1460

CAS Number: 110025-28-0

Notes: (E/Z)-Endoxifen is an active metabolite of tamoxifen (Item No. 13258) produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6.{29622,28212,29623} It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for estrogen receptors than tamoxifen.{29622} As the efficient conversion of tamoxifen to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.{29622,28212,29623}

• Artikelnummer: CAY21502-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21502-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK