EMA401, CAS 1316755-16-4

Formulation: A crystalline solid

Formal Name: (3S)-2-(2,2-diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinolinecarboxylic acid

Purity: ≥95%

Formula Markup: C32H29NO5

Formula Weight: 507,6

Shelf life (days): 1460

CAS Number: 1316755-16-4

Notes: EMA401 is an orally bioavailable and selective antagonist of the angiotensin II type 2 receptor (AT2; IC50s = 39.5 and 408,000 nM for rat recombinant AT2 and AT1, respectively).{47001} It inhibits capsaicin-induced calcium influx in cultured human dorsal root ganglion (hDRG) neurons (IC50 = 10 nM) and reduces neurite density and length in rat DRG neuronal cultures.{47002} EMA401 has analgesic effects in a rat model of neuropathic pain induced by chronic constriction injury.{47003}

• Artikelnummer: CAY22988-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22988-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK