Emamectin B1a, CAS 121124-29-6

Formulation: A solid

Formal Name: (4''R)-5-O-demethyl-4''-deoxy-4''-(methylamino)-avermectin A1a

Purity: ≥99%

Formula Markup: C49H75NO13

Formula Weight: 886,1

Shelf life (days): 1460

CAS Number: 121124-29-6

Notes: Emamectin B1a is a semisynthetic derivative of avermectin B1a (Item No. 22000).{35148} It binds to GABAA receptors (Ki = 17.6 nM in rat brain membranes), including those containing β1, β2, or β3 subunits (IC50s = 57, 210, and 49.8 nM for α1β1γ2, α1β2γ2, and α1β3γ2 subunits, respectively), and potentiates the GABA response.{35146} Emamectin B1a also binds to and inhibits glycine receptors (IC50 = 218 nM in rat spinal cord). Emamectin B1a induces mortality in 90% of S. exigua larvae in a diet incorporation assay at a dose of 1.067 ng/ml, which is approximately 1,500-fold more toxic than avermectin B1. It is effective against neonate S. eridania larvae in a foliage spray bioassay and when applied topically.

• Artikelnummer: CAY24060-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24060-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK