Enobosarm-d4, CAS 1202044-20-9

Formulation: A solid

Formal Name: (2S)-3-(4-cyanophenoxy-2,3,5,6-d4)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-propanamide

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C19H10D4F3N3O3

Formula Weight: 393,4

Shelf life (days): 1460

CAS Number: 1202044-20-9

Notes: Enobosarm-d4 is intended for use as an internal standard for the quantification of enobosarm by GC- or LC-MS. Enobosarm is a non-steroidal selective androgen receptor modulator (SARM; Ki = 0.0038 µM in a radioligand binding assay).{24834} It is a partial agonist of the androgen receptor (IC50 = 0.0364 µM in a transactivation assay) and inhibits the proliferation of 22Rv1, DU145, LNCaP, and VCaP prostate cancer cells (IC50s = 24.77, 44.55, 20.9, and 24.47 µM, respectively).{60912} Enobosarm (0.001 and 0.01 µM) inhibits lipogenesis in isolated rat adipocytes.{60913} It increases the weights of the prostate gland and seminal vesicles, markers of androgenic activity, and the levator ani muscle, a marker of anabolic activity, in castrated rats (ED50s = 0.12, 0.39, and 0.03 mg/day, respectively).{24834}

• Artikelnummer: CAY34687-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34687-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung