EPPTB, CAS 1110781-88-8

Formulation: A solid

Formal Name: N-(3-ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)-benzamide

Purity: ≥90%

Formula Markup: C20H21F3N2O2

Formula Weight: 378,4

Shelf life (days): 1460

CAS Number: 1110781-88-8

Notes: EPPTB is an antagonist of trace amine-associated receptor 1 (TAAR1; Ki = 0.9 nM for the mouse receptor).{61717} It selectively inhibits β-phenylethylamine-induced cAMP production in HEK293 cells expressing mouse TAAR1 over human or rat TAAR1 (IC50s = 27.5, 7,487, and 4,539 nM, respectively). EPPTB (10 nM) reduces decreases in the firing frequency of dopaminergic neurons induced by p-tyramine (Item No. 18601) in mouse ventral tegmental area (VTA) slices when used at a concentration of 10 nM.

• Artikelnummer: CAY34330-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34330-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK