Fexofenadine-d10 (hydrochloride), CAS 1215821-44-5

Formulation: A solid

Formal Name: 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl-d10)-1-piperidinyl]butyl]-α,α-dimethyl-benzeneacetic acid, monohydrochloride

Purity: ≥99% deuterated forms (d1-d10)

Formula Markup: C32H29D10NO4 • HCl

Formula Weight: 548,2

Shelf life (days): 1460

CAS Number: 1215821-44-5

Notes: Fexofenadine-d10 is intended for use as an internal standard for the quantification of fexofenadine (Item No. 18191) by GC- or LC-MS. Fexofenadine is a histamine H1 receptor antagonist (Ki = 10 nM).{27483} It reverses contraction of isolated rat tracheal strips induced by acetyl-β-methylcholine (Item No. 23092).{36897} Fexofenadine inhibits expression of IL-8 in TNF-α-stimulated HCT116 and COLO 205 cells.{36898} Oral administration of fexofenadine (2 and 10 mg/kg) reduces severity of colitis and phospho-IκB kinase activation in a mouse model of colitis induced by dextran sulfate sodium (DSS; Item No. 23250).

• Artikelnummer: CAY26115
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26115-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung