FITM, CAS 932737-65-0

Formulation: A crystalline solid

Formal Name: 4-fluoro-N-methyl-N-[4-[6-[(1-methylethyl)amino]-4-pyrimidinyl]-2-thiazolyl]-benzamide

Purity: ≥98%

Formula Markup: C18H18FN5OS

Formula Weight: 371,4

Shelf life (days): 1460

CAS Number: 932737-65-0

Notes: FITM is an antagonist of metabotropic glutamate receptor 1 (mGluR1; IC50 = 5.1 nM for the human receptor).{46556} It is selective for mGluR1 over mGluR2, mGluR5, and mGluR8 (IC50s = >10, 7, and >10 µM, respectively). FITM (0.3 mg/kg) decreases methamphetamine-induced hyperlocomotion in mice and reverses disruptions in prepulse inhibition induced by methamphetamine and ketamine in rats when administered at a dose of 1 mg/kg.

• Artikelnummer: CAY29219-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 29219-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK