Flavoxate-d5, CAS 2748541-85-5

Formulation: A solid

Formal Name: 3-methyl-4-oxo-2-phenyl-d5-4H-1-benzopyran-8-carboxylic acid, 2-(1-piperidinyl)ethyl ester

Purity: ≥99% deuterated forms (d1-d5)

Formula Markup: C24H20D5NO4

Formula Weight: 396,5

Shelf life (days): 1460

CAS Number: 2748541-85-5

Notes: Flavoxate-d5 is intended for use as an internal standard for the quantification of flavoxate (Item No. 19096) by GC- or LC-MS. Flavoxate is an inhibitor of L-type calcium channels and an antimuscarinic agent.{30978} It induces relaxation of potassium-precontracted isolated human urinary bladder detrusor muscle (IC50 = 2 µM) and reduces contractions induced by the acetylcholine receptor agonist carbachol (carbamoylcholine; Item No. 14486) or calcium in isolated rat detrusor strips.{30978,57774} Microinjection of flavoxate (0.68 µg/animal) into the oral pontine reticular nucleus inhibits reflex micturition in decerebrated cats, and intravenous or intracerebroventricular administration reduces isovolumetric rhythmic bladder contractions in rats.{57774} Formulations containing flavoxate have previously been used in the treatment of frequent or urgent urination, increased nocturnal urination, bladder pain, and urinary incontinence.

• Artikelnummer: CAY33816-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33816-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung