Fluphenazine (hydrochloride), CAS 146-56-5

Fluphenazine (hydrochloride), CAS 146-56-5
Artikelnummer
CAY23555-500
Verpackungseinheit
500 mg
Hersteller
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: 4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol, dihydrochloride

Purity: ≥95%

Formula Markup: C22H26F3N3OS • 2HCl

Formula Weight: 510,4

Shelf life (days): 1460

CAS Number: 146-56-5

Notes: Fluphenazine is a dopamine D1 and D2 receptor antagonist (Kis = 5 and 0.63 nM, respectively) and an active metabolite of fluphenazine decanoate (Item No. 39903).{40356} It also binds to histamine H1, serotonin 5-HT2A, and 5-HT2B receptors (Kis = 45, 17, and 82 nM, respectively).{40357} It acts as an inverse agonist at H1 and 5-HT2A receptors.{40357,40358} Fluphenazine is a typical antipsychotic compound. It induces extrapyramidal symptoms in animal models, including monkeys.{40359} Formulations containing fluphenazine have been used in the management of psychotic disorders.
Mehr Informationen
Artikelnummer CAY23555-500
Hersteller Cayman Chemical
Hersteller Artikelnummer 23555-500
Green Labware Nein
Verpackungseinheit 500 mg
Mengeneinheit STK
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