Fosphenytoin (sodium salt), CAS 92134-98-0

Formulation: A crystalline solid

Formal Name: 5,5-diphenyl-3-[(phosphonooxy)methyl]-2,4-imidazolidinedione, disodium salt

Purity: ≥98%

Formula Markup: C16H13N2O6P • 2Na

Formula Weight: 406,2

Shelf life (days): 1460

CAS Number: 92134-98-0

Notes: Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker, in vivo.{39387,39386,39385} It induces less tissue damage compared with two other phenytoin prodrugs in rats following subcutaneous and intramuscular administration.{39387} Fosphenytoin has anticonvulsant activity in a mouse model of maximal electroshock seizures similar to that of phenytoin (ED50s = 16 and 8 mg/kg, respectively).{39386} It also has antiarrhythmic activity in isolated guinea pig atria and in anesthetized dogs. Formulations containing fosphenytoin have been used in the treatment of status epilepticus.

• Artikelnummer: CAY23889-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23889-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK