Formulation: A solid
Formal Name: 7-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid, monosodium salt
Purity: ≥98%
Formula Markup: C27H29O9 • Na
Formula Weight: 520,5
Shelf life (days): 1460
CAS Number: 40786-08-1
Notes: FPL 55712 (sodium salt) is a leukotriene (LT) receptor antagonist.{57967} It inhibits the binding of LTD4 (Item No. 20310) to guinea pig lung homogenates (IC50 = 4 µM) and reduces LTD4-induced contraction of isolated guinea pig tracheal smooth muscle (pA2 = 1 µM). FPL 55712 (sodium salt) inhibits bronchoconstriction induced by LTD4, LTC4 (Item No. 20210), or LTE4 (Item No. 20410) in guinea pigs (ID50s = 2, 6, and 1 mg/kg, respectively).