Fuscin, CAS 83-85-2

Formulation: A solid

Formal Name: 9,10-dihydro-5-hydroxy-4,8,8-trimethyl-2H,4H-benzo[1,2-b:4,3-c']dipyran-2,6(8H)-dione

Purity: ≥95%

Formula Markup: C15H16O5

Formula Weight: 276,3

Shelf life (days): 1460

CAS Number: 83-85-2

Notes: Fuscin is a quinonoid fungal metabolite originally isolated from O. fuscum that has diverse biological activities.{46199,46200,46201} It inhibits binding of the ADP/ATP translocase inhibitor atractyloside (Item No. 14804) to rat liver mitochondria in an ADP-dependent manner when used at a concentration of 50 μM in a radioligand binding assay.{46199} Fuscin (20 μM) reduces the glutathione content of rat liver mitochondria to 28% of controls and inhibits NADH oxidation in sonicated pigeon heart mitochondria preparations in a concentration-dependent manner.{46200} It competes with macrophage inflammatory protein 1α (MIP-1α) for binding to CCR5 chemokine receptors in vitro with an IC50 value of 21 μM.{46201}

• Artikelnummer: CAY27485-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 27485-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK