γ-D-Glutamylglycine (trifluoroacetate salt), CAS 71822-19-0

Formulation: A solid

Formal Name: N-D-γ-glutamyl-glycine, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C7H12N2O5 • CF3COOH

Formula Weight: 318,2

Shelf life (days): 1460

CAS Number: 71822-19-0

Notes: γ-D-Glutamylglycine (γ-DGG) is an antagonist of the excitatory amino acids NMDA (Item No. 14581), quisqualate, kainate, and glutamate.{67019} It decreases the amplitude of excitatory post-synaptic potentials (EPSPs) in electrically stimulated rat hippocampal slices when used at a concentration of 200 mM. Subdural administration of γ-DGG inhibits NMDA-, kainate-, or quisqualate-induced paw biting, indicating antinociceptive activity, in mice (EC50s = 63, 9.5, and 31 µM, respectively).{67020} γ-DGG reduces sound-induced wild running and inhibits the clonic and tonic phases of sound-induced seizures in DBA/2 mice (ED50s = 0.058, 0.046, and 0.054 µmol, i.c.v., respectively).{67021}

• Artikelnummer: CAY36278-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36278-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK
• Methode: Reinstoffe