Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucinamide, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C54H81N13O14 • XCF3COOH

Formula Weight: 1136,3

Shelf life (days): 1460

Notes: Galanin (2-11) amide is a synthetic peptide fragment of the neuropeptide galanin and an agonist of the galanin-2 (GAL2) receptor (EC50 = 9.32 nM in a fluorescence imaging plate reader assay).{63146} It selectively binds to the GAL2 receptor (IC50 = 1.76 nM for the rat receptor) over the GAL1 receptor (IC50 = 879 nM for the human receptor) but does also bind to the GAL3 receptor (Ki = 271 nM for the rat receptor).{63146,63147} Intracerebroventricular administration of galanin (2-11) amide (1 nmol/animal) decreases immobility in the forced swim test in rats.{63149} It also reduces the hind paw mechanical pain threshold and increases the hind paw cold sensitivity threshold in rats.{63146}

• Artikelnummer: CAY34065-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34065-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK