Galnon (trifluoroacetate salt), CAS 1217448-19-5

Formulation: A crystalline solid

Formal Name: 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C40H46N4O6 • CF3COOH

Formula Weight: 792,9

Shelf life (days): 1460

CAS Number: 1217448-19-5

Notes: Galnon is a galanin (GAL) receptor agonist (KD = 2.9 µM in Bowes cells expressing GAL1 receptors).{53507} It inhibits forskolin-induced adenylate cyclase activity in rat hippocampal membranes (EC50 = 10 µM). Galnon (2 mg/kg) reduces the maximal seizure score and increases the latency to first seizure in a mouse model of seizure induced by pentylenetetrazole (PTZ; Item No. 18682). It reduces cocaine-induced motor activity and frontal cortex, but not nucleus accumbens, dopamine overflow, as well as blocks cocaine-primed reinstatement of cocaine-seeking behavior in rats.{53508} Galnon (1.5-5 mg/kg) reduces food intake in rats and mice.{53509}

• Artikelnummer: CAY29925-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 29925-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK