Ganglioside GD1a (porcine) (ammonium salt), CAS 12707-58-3

Formulation: A solid

Purity: ≥98%

Formula Markup: C84H146N4O39 • 2NH4 (for stearoyl)

Formula Weight: 1872,2

Shelf life (days): 1460

CAS Number: 12707-58-3

Notes: Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.{25490} It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin.{25484} This product contains ganglioside GD1a molecular species with primarily C18:0 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1546]

• Artikelnummer: CAY31707-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31707-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK