Ganoderic Acid DM, CAS 173075-45-1

Formulation: A solid

Formal Name: 3,7-dioxo-lanosta-8,24E-dien-26-oic acid

Purity: ≥98%

Formula Markup: C30H44O4

Formula Weight: 468,7

Shelf life (days): 1460

CAS Number: 173075-45-1

Notes: Ganoderic acid DM is a triterpenoid that has been found in G. lucidum and has diverse biological activities. {62327,62328,62329} It inhibits 5α-reductase and HMG-CoA reductase (IC50s = 10.6 and 9.5 µM, respectively) and binds to the ligand-binding domain of the androgen receptor in a fluorescence polarization assay.{62327,62328} Ganoderic acid suppresses osteoclastogenesis of RAW 264.7 cells when used at a concentration of 12.5 µM and is cytotoxic to K562 leukemia and PC3 prostate cancer cells (IC50s = 18.8 and 81.6 µM, respectively). It reduces ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice (ID50 = 0.08 mg/ear).{62329}

• Artikelnummer: CAY34536-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34536-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK