Gastrin I (human), CAS 10047-33-3

Formulation: A lyophilized powder

Formal Name: 5-oxo-L-prolylglycyl-L-prolyl-L-tryptophyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-tyrosylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide

Purity: ≥95%

Formula Markup: C97H124N20O31S

Formula Weight: 2098,2

Shelf life (days): 1460

CAS Number: 10047-33-3

Notes: Gastrin I is an endogenous, gastrointestinal peptide hormone that binds to cholecystokinin (CCK) receptors on human gastric leiomyosarcoma cells (IC50 = 0.9 nM) and in guinea pig gallbladder and pancreatic tissue (IC50s = 1.7 and 2.5 μM, respectively).{36434,36435} It increases levels of cytosolic calcium in isolated rabbit stomach parietal cells (EC50 = 11 nM) and stimulates pepsinogen secretion by isolated human peptic cells (ED50 = 30 nM).{36436,36437} Gastrin I increases histidine decarboxylase (HDC) activity ex vivo in fundic stomach mucosa homogenate and increases gastric acid secretion in vivo in rats when administered at a dose of 1 nmol/kg/h.{36438}

• Artikelnummer: CAY24457
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24457-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK