Formulation: A solid
Formal Name: N-[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]-glycine
Purity: ≥98%
Formula Markup: C28H47NO5
Formula Weight: 477,7
Shelf life (days): 1460
CAS Number: 863239-60-5
Notes: Glyco-obeticholic acid is an active metabolite of obeticholic acid (6-ECDCA; Item No. 11031), which is a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid (Item No. 10011286).{46303} Glyco-obeticholic acid is formed from obeticholic acid by glycine conjugation in the liver but can be reconverted back to obeticholic acid by microorganism-mediated deconjugation in the ileum and colon. It has been used as a precursor in the synthesis of bile acid analogs as agonists of the farnesoid X receptor (FXR) and TGR5.{45287}