Formulation: A crystalline solid
Formal Name: L-threonyl-L-prolyl-L-prolyl-L-threoninamide
Purity: ≥98%
Formula Markup: C18H31N5O6
Formula Weight: 413,5
Shelf life (days): 1460
CAS Number: 117928-94-6
Notes: GLYX 13 is a monoclonal antibody-derived tetrapeptide that acts as a partial agonist at the glycine site of the N-methyl-D-aspartate (NMDA) receptor.{33821,33823} It is active in vivo when administered intravenously, and it readily passes through the blood-brain barrier.{33821,33818} GLYX 13 has diverse effects in animals, as it blocks neuropathic pain, enhances learning and memory, and significantly reduces anxiety.{33823,33818,33820} GLYX 13 induces rapid antidepressant-like effects in animal models and rescued normal behavior in a rat model of autism.{33819,33822,33824}