GNTI (hydrochloride), CAS 351183-88-5

Formulation: A solid

Formal Name: [(4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,8a,9,14,14b-octahydro-1,8a-dihydroxy-4,8-methanobenzofuro[2,3-a]pyrido[4,3-b]carbazol-11-yl]-guanidine, dihydrochloride

Purity: ≥98%

Formula Markup: C27H29N5O3 • 2HCl

Formula Weight: 544,5

Shelf life (days): 1460

CAS Number: 351183-88-5

Notes: GNTI is a κ-opioid receptor antagonist (Ki = 0.18 nM).{53999} It is selective for κ-opioid receptors over µ- and δ-opioid receptors in radioligand binding assays (Kis = 36.9 and 70 nM, respectively). GNTI inhibits agonist-induced [35S]GTPγS binding in CHO cells expressing human κ-opioid receptors (pA2 = 10.4). In vivo, GNTI (0.3 mg/kg) induces scratching behavior in mice.{60000}

• Artikelnummer: CAY31597-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31597-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK