GW 766994, CAS 408303-43-5

Formulation: A solid

Formal Name: 4-[[[[[[(2S)-4-[(3,4-dichlorophenyl)methyl]-2-morpholinyl]methyl]amino]carbonyl]amino]methyl]-benzamide

Purity: ≥98%

Formula Markup: C21H24Cl2N4O3

Formula Weight: 451,4

Shelf life (days): 1460

CAS Number: 408303-43-5

Notes: GW 766994 is an antagonist of chemokine (C-C motif) receptor 3 (CCR3) with a Ki value of 13.8 nM in an assay of eosinophil chemotaxis induced by chemokine (C-C motif) ligand 11 (CCL11).{50126} It decreases CCL11-induced cyclin-dependent kinase 5 (Cdk5) and tau phosphorylation and production of amyloid β (1-42) (Aβ42) in isolated mouse hippocampal neurons when used at a concentration of 10 µM.{50127}

• Artikelnummer: CAY28431-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 28431-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK