Hexamethonium (bromide), CAS 55-97-0

Formulation: A crystalline solid

Formal Name: N1,N1,N1,N6,N6,N6-hexamethyl-1,6-hexanediaminium, dibromide

Purity: ≥98%

Formula Markup: C12H30N2 • 2Br

Formula Weight: 362,2

Shelf life (days): 1460

CAS Number: 55-97-0

Notes: Hexamethonium is a peripherally-acting nondepolarizing neuromuscular blocking agent that acts as an antagonist of nicotinic acetylcholine receptors (nAChRs).{46022,42108} It decreases acetylcholine release induced by carbamoylcholine (Item No. 14486) in isolated cat superior cervical ganglion when used at concentrations of 27.4 and 54.8 µg/ml.{46023} It also decreases mean arterial pressure in unanesthetized rats when administered at a dose of 40 mg/kg.{46024} Intraventricular administration of hexamethonium (18 ng, i.c.v.) induces signs of nicotine abstinence, including shaking, writhing, and chewing in nicotine-dependent rats.{46025} Formulations containing hexamethonium were previously used in the treatment of hypertension.

• Artikelnummer: CAY25505-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25505-100
• Green Labware: Nein
• Verpackungseinheit: 100 g
• Mengeneinheit: STK