Formulation: A crystalline solid
Formal Name: L-histidyl-2-methyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide
Purity: ≥98%
Formula Markup: C47H58N12O6
Formula Weight: 887
Shelf life (days): 1460
CAS Number: 140703-51-1
Notes: Hexarelin is a synthetic hexapeptide agonist of the growth hormone secretagogue receptor (GHS-R).{61220,61221} It selectively binds to GHS-R over CD36 (IC50s = 15.9 and 2,080 nM, respectively).{61220} Hexarelin (300 µg/kg, s.c.) increases plasma growth hormone levels in neonatal rats.{61221} It also improves left ventricular function and reduces fibrosis in a mouse model of myocardial ischemia induced by transient ligation of the left descending coronary artery (LAD) when administered at a dose of 0.3 mg/kg per day.{61222}